March/April 2022

Table of Contents


  • Editorial Pieces of the puzzle

    Timothy F. Kosinski

    2022 March/April;70(2):5.

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  • Ethics Civility as a function of leadership

    Toni M. Roucka

    2022 March/April;70(2):6-8.

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  • Pharmacology Acetaminophen: how safe is it?

    Mark Donaldson
    Jason H. Goodchild

    2022 March/April;70(2):9-13.

    Full Article (PDF)
  • 2021 Reviewers General Dentistry expresses its gratitude to 2021 peer reviewers

    2022 March/April;70(2):74-77.

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  • Oral Diagnosis Yellowish papillary lesion and Exposed hard tissue

    Tanya M. Gibson

    2022 March/April;70(2):78,80.

    Full Article (PDF)
  • Self-Instruction Answers Exercises No. GD471, GD472, and GD473 from the March/April 2021 issue

    2022 March/April;70(2):79.

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Clinical Articles: Focus on Oral and Systemic Cancers


    Oral Medicine, Oral Diagnosis, Oral Pathology Accuracy of leukoplakia diagnoses: a retrospective study

    Samantha Nelson
    Mariah Heft-Allen
    Nagamani Narayana

    This retrospective study aimed to assess the diagnostic accuracy of clinicians identifying leukoplakia and the diagnostic terminology used to indicate leukoplakic lesions. The percentage of histologically correct diagnosis of leukoplakia improved over the years studied, but clinicians continued to misclassify identifiable pathoses such as lichen planus, lichenoid mucositis, and fibroma as leukoplakia. 

    2022 March/April;70(2):14-17.

    Full Article (PDF)
    Self-Instruction Exercise No. GD489
  • Oral Medicine, Oral Diagnosis, Oral Pathology Peri-implant squamous cell carcinoma mimicking peri-implantitis: a case report

    Fazele Atarbashi-Moghadam
    Hassan Mir Mohammad Sadeghi
    Saede Atarbashi-Moghadam

    This article presents the case of a patient with a peri-implant oral squamous cell carcinoma (OSCC) mimicking peri-implantitis. After implant removal did not resolve a radiolucency around a loosened implant, histopathologic and immunohistochemical analyses of biopsy specimens resulted in a diagnosis of OSCC, highlighting the importance of the differential diagnosis for early detection of OSCC.

    2022 March/April;70(2):19-21.

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    Oral Medicine, Oral Diagnosis, Oral Pathology Review of oral mucositis treatment guidelines with an emphasis on laser therapy

    Christopher J. Walinski
    Sabrina M. Mellusi 
    Ashley E. Brodeur
    Emily Marchick
    Daniel Katz
    Meade van Putten

    This article summarizes the findings of systematic reviews conducted by the Multinational Association of Supportive Care in Cancer and the International Society of Oral Oncology on interventions to prevent and treat oral mucositis arising from radiotherapy and chemotherapy. A case of oral mucositis treated with lasers is presented to illustrate a promising new treatment. 

    2022 March/April;70(2):22-26.

    Full Article (PDF)
    Self-Instruction Exercise No. GD490
  • Oral Medicine, Oral Diagnosis, Oral Pathology Adenocarcinoma of mammary origin in the maxillary gingiva: a case report and brief literature review

    Ana Carolina dos Santos Menezes
    Lísia Daltro Borges Alves
    Fernanda Vieira Heimlich
    Rachel de Carvalho Silveira de Paula Fonseca
    Héliton Spíndola Antunes
    Débora Lima Pereira

    This case report describes a patient with previously diagnosed and treated invasive ductal breast carcinoma who developed a metastatic lesion in the maxillary gingiva. In addition, a literature review discusses articles pertaining to metastatic breast cancer manifestations in the gingiva. 

    2022 March/April;70(2):28-32.

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  • Oral Medicine, Oral Diagnosis, Oral Pathology Essentials of oral manifestations of leukemia for the dental practitioner

    Patricia Barros
    Mohammed N. Islam
    Sarah G. Fitzpatrick
    Donald M. Cohen
    Indraneel Bhattacharyya
    Saja A. Alramadhan

    This retrospective case series describes the oral manifestations of leukemia to aid in the earlier diagnosis or recognition of relapse. In this cohort of 10 patients, 6 cases occurred in men, and the mean age of the patients was 58 years. The gingiva was the most frequently biopsied site. Importantly, 4 of the patients (40%) had no prior diagnosis of leukemia.  

    2022 March/April;70(2):33-36.

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  • Oral Medicine, Oral Diagnosis, Oral Pathology Oral soft tissue manifestation of multiple myeloma after kidney transplantation: a case report

    Nicole Piscatelli
    Nicole Hinchy
    Jennifer Frustino
    Laura Reed
    James Zemer
    Naheed Alam
    Paul Hosking
    Maureen Sullivan

    This case report describes oral soft tissue lesions as the first signs of multiple myeloma following a solid-organ transplantation. Awareness of the patient’s medical history and an understanding of the maxillofacial manifestation of multiple myeloma are important to ensure diagnosis in the early stages of disease.

    2022 March/April;70(2):37-40.

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Clinical Articles


    Oral Medicine, Oral Diagnosis, Oral Pathology Scleroderma and multiple teeth with invasive cervical resorption: is there a connection?

    Jonathan E. Journo
    Karl F. Woodmansey
    Ryan M. Walsh

    Invasive cervical resorption occurred in multiple teeth in a patient with scleroderma, a chronic connective tissue disease. This case report details the findings of imaging studies and discusses the possible relationships between these diseases.

    2022 March/April;70(2):41-44.

    Full Article (PDF)
    Self-Instruction Exercise No. GD491
  • Oral Medicine, Oral Diagnosis, Oral Pathology Sublingual varicosity as a possible indicator of hypertension

    Maryam Baharvand
    Hamed Mortazavi
    Mojgan Eshaghian
    Homa Mirzaei

    The aim of this study was to investigate whether an association exists between the severity of sublingual varices and the presence of hypertension. Logistic regression analysis showed that patients with more pronounced sublingual varicosity had a greater risk of hypertension than did patients with few varices.

    2022 March/April;70(2):46-49.

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  • Implants Stability of mandibular implants with Morse taper and external hexagon connections placed under immediate loading: a longitudinal clinical study

    Oriana Elara Barelli Paganelli
    Pâmela Letícia Santos
    Rubens Spin-Neto
    Valfrido Antonio Pereira Filho
    Rogério Margonar

    This clinical study compared the stability of mandibular implants with Morse taper and external hexagon connections placed under an immediate loading protocol. The results suggested that both Morse taper and external hexagon prosthetic connections provide good stability for immediate functional loading. 

    2022 March/April;70(2):50-54.

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  • Oral Medicine, Oral Diagnosis, Oral Pathology Spontaneous medication-related osteonecrosis of the jaw: a bimodal treatment approach

    Joseph A. DeBenedictis

    Spontaneous medication-related osteonecrosis of the jaw was successfully treated with a bimodal nonsurgical and surgical approach in a patient with a complicated medical history and multiple medical considerations. The initial nonsurgical approach allowed time for the influence of antiresorptive medication to dissipate and ensured optimal conditions for surgery. 

    2022 March/April;70(2):55-58.

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  • Basic Science Cone beam computed tomography in the detection of reactional osteogenesis of the maxillary sinus: a case report

    Brunno Santos de Freitas Silva
    Andressa Hajjar Daher
    Amanda Luysa Roriz Pinto
    Eduarda Helena Souza e Silva
    Rogério Ribeiro de Paiva
    Wilson José Mariano-Júnior
    Fernanda Paula Yamamoto-Silva

    This case report describes reactional osteogenesis associated with the residual roots of the maxillary left first molar. Volumetric analysis established the diagnosis and facilitated removal of the focus of infection associated with the reactional bone formation. Three-dimensional imaging examinations of the maxillary sinus are crucial in the presence of infectious processes in the posterior region of the maxilla.

    2022 March/April;70(2):59-61.

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  • Periodontics Role of professional expertise in the decision-making process for periodontally compromised teeth

    Natan Mecler
    Rafael Martins Rodrigues
    Alexandre Marques Paes da Silva
    Antônia Cristiane Fernandes
    Bernardo Mattos Almeida
    Lucio de Souza Gonçalves
    Antonio Canabarro
    Dennis de Carvalho Ferreira

    To evaluate factors that may influence decision-making about the treatment of periodontally compromised teeth, researchers presented dental students and dentists with 2 clinical scenarios, including radiographs. For the majority of participants, the decision in both scenarios was to maintain the compromised teeth rather than extract; however, the results suggested that that the years of experience of the individual and the specialty of the practitioner can influence decision-making. 

    2022 March/April;70(2):62-68.

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  • Endodontics Multidisciplinary management of a type III palatoradicular groove: an atypical presentation

    Jaganathan Vijayakumar
    Shekar Shobana
    Mahendran Kavitha

    This article describes the management of a maxillary lateral incisor with complicated anatomy. After unsuccessful endodontic treatment, radiography revealed a palatoradicular groove and an accessory root. Spiral computed tomography confirmed that the accessory root had no root canal, so it was maintained in retreatment, and the groove in the main root was saucerized and restored with glass ionomer cement.

    2022 March/April;70(2):69-72.

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