General Dentistry is the award-winning, peer-reviewed journal of the Academy of General Dentistry. Published bimonthly, General Dentistry features clinical articles spanning the breadth of topics relevant to general dentists, including unique diagnostic case reports, novel solutions to common treatment dilemmas, evidence-based best practices, and the science to help you choose the best materials, technology and procedures for your patients and your practice.
Table of Contents
Departments
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Editorial Cutting-edge dentistry
Timothy F. KosinskiFull Article (PDF)
2025 September/October; 73(5):5.
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Pharmacology Doxycycline: 3 new things about an old drug
Mark DonaldsonFull Article (PDF)
Jason H. Goodchild
2025 September/October; 73(5):6-10.
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Orofacial Pain Understanding cracked tooth syndrome: diagnosing nondental pain in dentistry
Stanley MarkmanFull Article (PDF)
Amey G. Patil
2025 September/October; 73(5):11-13.
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Prosthodontics The crucial second appointment in full-arch removable prosthesis cases
Samuel M. StrongFull Article (PDF)
2025 September/October; 73(5):14-16.
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Public Health Understanding and preparing for our aging patient population
Larry N. WilliamsFull Article (PDF)
2025 September/October; 73(5):17-19.
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Implants Tooth replacement from extraction to restoration. 3. Second-stage and impression procedures
Marcus CowanFull Article (PDF)
2025 September/October; 73(5):20-24.
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Oral Diagnosis Heart-shaped radiolucency and Gingival yellow spot
Tanya M. GibsonFull Article (PDF)
2025 September/October; 73(5):78,80.
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Self-Instruction Answers Exercises No. GD533, GD534, and GD35
2025 September/October; 73(5):79.Full Article (PDF)
Clinical Articles
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Oral Medicine, Oral Diagnosis, Oral Pathology What every dentist needs to know about cannabis use and head and neck cancer
John K. BrooksFull Article (PDF)
Muhammad Hamza
Maureen A. Fitzpatrick
Nasir Bashirelahi
The objective of this review is to examine the association between cannabis exposure and head and neck cancer (HNC), including a discussion of epidemiologic findings and molecular mechanisms. A recent cohort study established that individuals with cannabis-related disorder have a significantly increased risk for HNC. Dental healthcare providers should inform their patients that heavy cannabis use may be associated with an increased risk of HNC.
2025 September/October; 73(5):25-27.
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SELF-INSTRUCTION
Periodontics A comparative evaluation of serum and salivary levels of apelin in chronic periodontitis associated with obesity and type 2 diabetes mellitus
Jammula Surya PrasannaFull Article (PDF)
Duddukuri Hema
This study assessed levels of the biomarker apelin in patients with obesity, type 2 diabetes mellitus, and chronic periodontitis (CP). Apelin levels in patients with CP were generally lower than levels in individuals without CP. Individuals with obesity or obesity and diabetes showed higher levels of serum apelin compared with healthy individuals. A significant negative correlation was observed between serum apelin and periodontal parameters in specific subgroups.
2025 September/October; 73(5):28-34.
Self-Instruction Exercise No. GD550 -
SELF-INSTRUCTION
Oral Medicine, Oral Diagnosis, Oral Pathology Nonodontogenic cysts and pseudocysts of the oral cavity: a retrospective study of 218 cases
Saede Atarbashi-MoghadamFull Article (PDF)
Nastaran Niknam
Seyed Sepehr Mirebeigi-Jamasbi
This retrospective cross-sectional study determined the frequencies of nonodontogenic cysts and pseudocysts among 7036 patients evaluated over a 20-year period. Nonodontogenic cysts were found in 0.5% of all referred patients, while pseudocysts were identified in 2.6%. Significant relationships were found between cyst type and patient sex, patient age, and oral location of the cyst.
2025 September/October; 73(5):36-40.
Self-Instruction Exercise No. GD551 -
Basic Science Influence of a Bis-GMA–free universal adhesive system on enamel bond strength to ceramic brackets
Aline Júnia OliveiraFull Article (PDF)
Victor Angelo Martins Montalli
Jurandir Antonio Barbosa
Roberta Tarkany Basting
This in vitro study evaluated the shear bond strengths and Adhesive Remnant Index scores of 2 types of ceramic orthodontic brackets bonded to enamel using adhesives with and without bis-GMA. No statistically significant differences in bond strength were observed among the adhesives, but the Bis-GMA–free system (containing 10-MDP) showed the highest adhesive retention for both bracket types.
2025 September/October; 73(5):42-47.
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Oral Medicine, Oral Diagnosis, Oral Pathology Multidisciplinary approach to diagnosis and management of lymphadenopathy in a patient with mucous membrane pemphigoid: a case report
Heba TurkstaniFull Article (PDF)
Eman Alamodi
Eric T. Stoopler
Mel Mupparapu
Temitope T. Omolehinwa
This report describes the case of a patient with mucous membrane pemphigoid of the skin who developed oral mucosal blisters and gingival bleeding. Incidental findings during the routine head and neck examination led to a diagnosis of mantle cell lymphoma, reinforcing the importance of thorough, routine head and neck examinations for patients with autoimmune blistering diseases.
2025 September/October; 73(5):48-53.
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Oral and Maxillofacial Surgery Root migration after coronectomy of impacted mandibular third molars: case reports
Gustavo Henrique de Souza SilvaFull Article (PDF)
Enzo Balestrero
Jéssica Lemos Gulinelli
Pâmela Leticia dos Santos
Coronectomy is recommended to reduce the risk of nerve complications when impacted third molars are located near the inferior alveolar nerve. Root migration is among the possible sequelae of this technique, but a report of 3 clinical cases of root migration after coronectomy demonstrates that the procedure is a safe, viable alternative to conventional extraction.
2025 September/October; 73(5):54-58.
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Oral Medicine, Oral Diagnosis, Oral Pathology Malignant transformation of oral lichen planus after 6 years: a case report
Patrícia Peres Iucif PereiraFull Article (PDF)
Amanda Bandeira de Almeida
João Adolfo Costa Hanneman
Eduardo Pereira Guimarães
Henrique de Carvalho Petean
Daiana Moreira Mendes Rozendo
Alessandro Antônio Costa Pereira
This case report describes a possible occurrence of malignant transformation of oral lichen planus in a woman who was treated with a topical corticosteroid. Five years after treatment, after ceasing to attend follow-up examinations, she developed oral squamous cell carcinoma. Patients should be advised about the importance of follow-up examinations, as malignant transformation of oral lichen planus may occur.
2025 September/October; 73(5):59-63.
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Special Patient Care Oral health in relation to manifestations and severity of cystic fibrosis: a cross-sectional study
Ana Carolina Evangelista ColafêminaFull Article (PDF)
Aline Cristina Gonçalves
Cecília Regina Frazatto
Camila Real Delegá Rodrigues
Antônio Fernando Ribeiro
José Dirceu Ribeiro
Márcio Ajudarte Lopes
This study assessed the prevalence of oral health conditions in 82 patients with cystic fibrosis. The most significant oral health problem was dental enamel defects, which affected nearly half the population. Gingivitis was also prevalent in this population, and patients with higher gingival index scores were more likely to develop exacerbation of pulmonary symptoms.
2025 September/October; 73(5):64-71.
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Fixed Prosthodontics Influence of beverage solutions on the microhardness and surface roughness of provisional fixed denture materials
Eduardo Comeron PieraliniFull Article (PDF)
Renan Aparecido Fernandes
Henrico Badaoui Strazzi-Sahyon
Anelise Rodolfo Ferreira Pieralini
Paulo Henrique Dos Santos
Sabrina Pavan
This study assessed the effects of in vitro aging with different beverage solutions on the hardness and surface roughness of provisional fixed denture materials. Beverage solutions significantly influenced the mechanical properties of the materials, with Protemp 4 bis-acryl–based resin material demonstrating hardness and surface roughness values that were less affected by aging.
2025 September/October; 73(5):72-77.
